Shelby Storm, Madeline Pflasterer-Jennerjohn, Robert Slater, Rachel Linderman, Jeong W. Pak, David Lopez, Barbara A. Blodi, Amitha Domalpally Abstract Purpose: Ellipsoid zone (EZ) loss is increasingly used as an endpoint in geographic atrophy (GA) trials, …
Artificial Intelligence
Real World Validation of Optos AI Algorithm for GA area Measurement
Reeva Faisal, Caleb Pacheco, Robert Slater, Mohammed S. Younis, Jomol Matthew, Marine Nalbandyan, Amitha Domalpally, Roomasa Channa Abstract Purpose: Optos ultrawide field imaging is widely used in routine care to monitor Geographic Atrophy (GA) progression …
AI-based Multilayer OCT Segmentation Model for AMD
Rachel Linderman, Aadhi1 Balasubramanian, Madeline Pflasterer-Jennerjohn, Lucas Maakested, Jeong W. Pak, Robert Slater, Roomasa Channa, Barbara A. Blodi, Amitha Domalpally Abstract Purpose: To assess an artificial intelligence (AI)-based OCT segmentation with the ability to segment …
UWF-Based Diabetic Retinopathy (DR) Prescreening Using a Novel Patch-Based AI Model
Nancy Barrett, Varsha Satish, Robert Slater, Thomas Saunders, Rachel Linderman, Barbara Blodi, Amitha Domalpally Abstract Purpose: Ultra-widefield (UWF) color photographs are widely used in clinical practice and clinical trials because they capture the entire retina …
AI-based Multilayer OCT Segmentation Model For Macular Edema
Justin Bitner, Rachel Linderman, Aadhi Balasubramanian, Madeline Pflasterer-Jennerjohn, Jeong W. Pak, Robert Slater, Roomasa Channa, Lucas Maakested, Barbara A. Blodi, Amitha Domalpally Abstract Purpose: To train and assess an artificial intelligence (AI)-based OCT segmentation with …
Real World Deployment of a Prescreening Algorithm for Geographic Atrophy
Thomas Saunders, Robert Slater, Roomasa Channa, Barbara A. Blodi, Amitha Domalpally Abstract Purpose: Area of geographic atrophy (GA) is a primary enrollment criterion in clinical trials. Current practices rely on clinicians to screen subjects for …
AI-enabled multi-disease OCT segmentation
Caleb Pacheco, Rachel E. Linderman, Madeline Pflasterer-Jennerjohn, Mark Banghart, Robert D. Slater, Roomasa Channa, Amitha Domalpally Abstract Purpose: To develop an artificial intelligence (AI) enabled OCT segmentation algorithm specifically tailored for diabetic macular edema (DME), …
Deep Learning-Based Quantification of GA Area on OCT Scans
Rushi N. Mankad, Madeline Pflasterer-Jennerjohn, Rachel E. Linderman, Robert Slater, Amitha Domalpally Abstract Purpose: The consensus of Atrophy (CAM) criteria provides a robust framework for evaluating geographic atrophy (GA) with optical coherence tomography (OCT) scans. …
Artificial Intelligence (AI) enabled pre-screening for Diabetic Retinopathy (DR) clinical trials
Nancy Barrett, Robert Slater, Rachel E. Linderman, Rick Voland, Claire Calhoun, Jennifer K. Sun, Barbara A. Blodi, Amitha Domalpally, with the DRCR Retina Network Abstract Purpose: Preventive strategies to slow progression of diabetic retinopathy (DR) …
AI-based Measurement of GA Area for Screening In Clinical Trials
Mohammed Younis, Robert D. Slater, Caleb Pacheco, Sairi Zhang, Rick Voland, Rachel E. Linderman, Roomasa Channa, Amitha Domalpally Abstract Purpose: To develop and validate a transfer learning model for measuring geographic atrophy (GA) area using …
Prediction of Geographic Atrophy Enlargement using Various Deep Learning Approaches (2023)
Amitha Domalpally, Robert Slater, Mark Banghart, Roomasa Channa, Donald S. Fong, Barbara Blodi Abstract Purpose: Fundus autofluorescence (FAF) imaging is used to monitor geographic atrophy (GA) growth inclinical trials. There is significant variability in the …
Influence of Race on Training Data Quality for Artificial Intelligence (AI) Algorithms (2022)
Amitha Domalpally, Rick Voland, Robert Slater, Ellie Corkery, Pamela Vargo, Rebecca Kuhtz, James Reimers, Roomasa Channa, Barbara Blodi Abstract Purpose: Diabetic retinopathy (DR) severity level is evaluated from stereoscopic 7-field color photographs by masked graders …
Implementation of a Large-Scale Retinal Image Curation Workflow Using Deep Learning Framework (2022)
Rohit Balaji, Jen Heathcote, Robert Slater, Nancy Barrett, Rick Voland, Vesna Tomic, Jared McDonald, Barbara A. Blodi, Amitha Domalpally Abstract Purpose: The development of artificial intelligence (AI) algorithms for analyzing retinal pathologies requires training based …
Artificial Intelligence (AI) enabled pre-screening for Diabetic Retinopathy (DR) clinical trials (2022)
Nancy Barrett, Robert Slater, Roomasa Channa, Barbara Blodi, Amitha Domalpally Abstract Purpose: Preventive therapies to reduce progression of non-proliferative DR (NPDR) to proliferative DR are underway. Clinical trial enrollment criteria typically include a baseline DR …